Biopharmaceutics and Biologic Drugs
Biopharmaceutics is defined as the study of factors that influencing rate and amount of drug which reaches the systemic circulation and use of this information to optimize the therapeutic efficacy of the drug products. The process of movement of drug from site of administration to systemic circulation is called as absorption. The concentration of drug in plasma, onset of action, intensity and duration of response depend upon the bioavailability of drug from its dosage form. Bioavailability is defined as the rate and extent (amount) of drug absorption which indicates active effect. The biological medical product indulges in manufacturing or extraction or semi synthesizing the pharmaceutical drug product from biological sources. The biologic drug is manufactured in all the living system such as plant cells or animal cells, or microorganism. Most of these biologics are produced with the help of Recombinant DNA technology.
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